Research Interests

我們的研究工作主要著重於化學生物及新藥研發。從瞭解致病基因的功能及機制去設計並合成小分子來進一步研究其與標的物的作用,進而研發出新的檢測方法及新 藥。目前重點放在瞭解醣分子在細胞表面所扮演的角色,醣蛋白合成方法的發展,醣晶片的設計與應用,及酵素抑制劑的設計與合成。希望將來能發展新的藥物以供 抗癌、抗病毒與抗細菌的研究。

 

RESEARCH INTERESTS: Chemical Biology and Drug Discovery

Research in the Wong lab encompasses a broad spectrum of bioorganic and synthetic chemistry. Development of small molecules targeting proteins and RNA has been performed to investigate how small molecules interact with biologically important molecules and in turn, learn more about the function of those molecules. Development of both synthetic and bioorganic strategies is also paramount to our research. Programmable one-pot reactions are being developed for the synthesis of complex oligosaccharides and glycoarrays and compliment new strategies for the assembly of glycoproteins, vaccines and other biologically active molecules to tackle major problems in biology, especially associated with cancer, infectious diseases and Immune system.

 

資料來源:

http://www.genomics.sinica.edu.tw/index.php/tw/wong-chi-huey-http://www.scripps.edu/wong/